Skin Lightening Glabridin 5%-98% CAS NO.59870-68-7

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Min.Order: 1 Kilogram
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Product Details

Keywords

Glabridin
Skin Lightening
Skin Lightening Glabridin 5%-98%

Quick Details

ProName: Skin Lightening Glabridin 5%-98%
CasNo: 59870-68-7
Molecular Formula: C20H20O4
Appearance: White and Red-brown Powder
Application: Major function Skin Lightening Glabri...
DeliveryTime: Within 3 weekdays after payment
PackAge: 1kg with double plastic container insi...
Port: Tianjin; Beijing; Shanghai; any port
ProductionCapacity: 20 Kilogram/Month
Purity: 5%-98%
Transportation: 1kg with double plastic container insi...
LimitNum: 1 Kilogram
Plant of Origin: Licorice Root Skin Lightening Glabridi...
Testing Method: HPLC
Product Ecification: 5%-98%
Heavy Metal: 重金属：≤10ppm Arsenic salt 砷盐：≤2ppm
Voluntary Standards: In House
Molecular Formula: C20H20O4
Molecular Weight: 324.36
Certification: ISO,HACCP,KOSHER,GMP,FDA
Chemical classification: Flavonoid Glabridin For Skin Lightenin...
Test Method: HPLC
Colour: White and Red-brown
Character: Powder
Odor: Characteristic
Purity: 5%-98%
Grade: Cosmetic Grade
Place of Origin: Shaanxi, China (Mainland)

Superiority

Major function

Skin Lightening Glabridin 40% has anti-inflammatory,

Skin Lightening Glabridin 40%has anti-oxidation,

Skin Lightening Glabridin 40%has anti-aging,

Skin Lightening Glabridin 40%has UV abortion,

Skin Lightening Glabridin 40%has skin whitening,

Skin Lightening Glabridin 40%has spot removing.

Product character

Skin Lightening Glabridin 40%is the White crystalline Powder , dissolved in methanol, ethanol, propylalcohol,
propanediol and 1,3-butanediol.

Specfication:5%-98%

Application fields

Skin Lightening Glabridin 40%is widely used in cosmetic product as cream, paste, water solution and emulsion.

Details

Item of test	Standard
Physical&chemical Control
Assay(BY- HPLC)Content	5.0%-98.0%
Appearance	Red-brown or White Powder
Loss on drying	5.0%
Residue on ignition	1.0%
Heavy metals	10ppm
Arsenic salt	2ppm
Microbiological control
Total of bacterium	800CFU/g
Yeast&Mold	80CFU/g
Salmonella	Negative
E.coli	Negative

Product description

Abstract

Skin Lightening Glabridin 40% is an isoflavan from licorice root, which is a common component of herbal remedies used for treatment of menopausal symptoms. Past studies have shown that glabridin resulted in favorable outcome similar to 17β-estradiol (17β-E2), suggesting a possible role as an estrogen replacement therapy (ERT).

This study aims to evaluate the estrogenic effect of glabridin in an in-vitro endometrial cell line -Ishikawa cells via alkaline phosphatase (ALP) assay and ER-α-SRC-1-co-activator assay. Its effect on cell proliferation was also evaluated using Thiazoyl blue tetrazolium bromide (MTT) assay. The results showed that glabridin activated the ER-α-SRC-1-co-activator complex and displayed a dose-dependent increase in estrogenic activity supporting its use as an ERT. However, glabridin also induced an increase in cell proliferation.

When glabridin was treated together with 17β-E2, synergistic estrogenic effect was observed with a slight decrease in cell proliferation as compared to treatment by 17β-E2 alone. This suggest that the combination might be better suited for providing high estrogenic effects with lower incidences of endometrial cancer that is associated with 17β-E2.

Skin Lightening Glabridin 40% is a nature skin whitening agent extracted from special licorice and has ability of inhibit the activity of Tyrosinase,

Skin Lightening Glabridin 40% has ability to inhibit dopachrome tautomerase and activity of DHICA oxidation enzyme.

Skin Lightening Glabridin 40% is a green, highly efficient skin whitening agent and additive in cosmetic product, has similar ability as SOD to remove radicals and ability to antioxidant properties similar like Vitamin E.